This sexually transmitted disease is characterized by varying manifestations including urethritis, cervicitis, or salpingitis. It may be asymptomatic in some persons or may become disseminated. Laboratory detection of Neisseria gonorrhoeae in clinical specimens confirms the diagnosis. Other methods of laboratory confirmation include detection of antigen or nucleic acid in specimens or observation of gram-negative intracellular diplococci in a urethral smear obtained from a male patient.

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