Patients with hemophilia A, factor VIII deficiency, account for 85 percent of patients with hemophilia. This X-linked, recessive disorder occurs in 1 in 10,000 live male births. Hemophilia B, factor IX deficiency, is also an X-linked recessive disorder and occurs in 1 in 25,000 to 30,000 live male births. Thirty percent of affected patients have no family history of hemophilia; spontaneous mutations are believed to be responsible. Females are generally carriers of hemophilia A or B, have 50 percent of normal factor VIII or factor IX activity, and are asymptomatic. On occasion, due to extreme lyonization, a female carrier can have lower factor VIII or factor IX levels and have clinical manifestations of the disease.

Cure Your Yeast Infection For Good

Cure Your Yeast Infection For Good

The term vaginitis is one that is applied to any inflammation or infection of the vagina, and there are many different conditions that are categorized together under this ‘broad’ heading, including bacterial vaginosis, trichomoniasis and non-infectious vaginitis.

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