If penicillin allergic

(Note two drug therapy)

1. Clindamycin 300-450 mg PO qid [B] PLUS (for Eikenella coverage)

1. Ciprofloxacin (Cipro) 500 mg PO bid [C]

2. TMP/SMX DS (Septra DS, Bactrim DS) 1 tablet PO bid [C; D in 3rd trimester] Course: 7-10 days

Organisms: S. viridans, Eikenella corrodens, Staph sp., Corynebacterium, anaerobes (Peptostreptococcus, Bacteroides)


1. Ampicillin/sulbactam (Unasyn) 1.5 g IV q6h [B]

3. Ticarcillin/clavulanate (Timentin) 3.1 g IV q6h [B]

4. Piperacillin/tazobactam (Zosyn) 3.375 g IV q6h [B]

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