Jaundice (Table 112:5) may appear at varying times during the neonatal period and requires a complete diagnostic evaluation. Jaundice during the first 24 h rarely presents to the emergency department. The commonest causes of jaundice seen in the emergency department are physiologic jaundice, jaundice due to sepsis, or breast-milk jaundice. Occasionally, infants with hemolysis due to autoimmune congenital causes may present to the emergency department.

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