Ongoing osmotic diuresis may cause significant depletion of magnesium stores (from bone) and hypomagnesemia. Hypomagnesemia may inhibit parathyroid hormone secretion, causing hypocalcemia and hyperphosphatemia. Symptomatic hypomagnesemia in DKA (hyperreflexia, positive Chvostek or Trousseau signs) is rare, as is the need for intravenous therapy. If serum magnesium is <1.2 mg/dL or symptoms are suggestive of hypomagnesemia, magnesium can be given orally in the form of magnesium oxide or parenterally as magnesium sulfate. It is recommended to monitor serum magnesium and calcium on presentation and 24 h into therapy unless symptoms suggestive of hypomagnesemia or hypocalcemia occur.

Essentials of Human Physiology

Essentials of Human Physiology

This ebook provides an introductory explanation of the workings of the human body, with an effort to draw connections between the body systems and explain their interdependencies. A framework for the book is homeostasis and how the body maintains balance within each system. This is intended as a first introduction to physiology for a college-level course.

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