The use of factor replacement therapy in hemophilic patients with inhibitors is guided by the inhibitor titer (number of BIA units) and the type of response the patient has to factor VIII concentrates. This anamnestic response is usually either a rapid increase in the inhibitor titer within 2 to 3 days (high responders) or a low response where the inhibitor increases little or none (low responders). T§b.!e,...212-5 outlines the treatment options available for treatment of hemophilia A patients with inhibitors.
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