1. Azithromycin (Zithromax) 2 g PO single dose is considered effective for N. gonorrhoeae and Chlamydia, but GI discomfort is common.

2. May consider prophylaxis for T. vaginalis with metronidazole (Flagyl) 2 g PO single dose [B, contraindicated 1st trimester]

3. Recommend initial testing for GC, Chlamydia, HIV, syphilis, and pregnancy.

4. Ofloxacin (Floxin) and ciprofloxacin (Cipro) do not have activity against incubating syphilis.

1. Ceftriaxone (Rocephin) 125 mg IM single dose [B]

2. Cefotaxime (Claforan) 500 mg IM single dose [B]

3. Cefixime (Suprax) 400 mg PO single dose [B] (not for pharyngeal infection)

4. Ciprofloxacin (Cipro) 500 mg PO single dose [C]

5. Ofloxacin (Floxin) 400 mg PO single dose [C]

6. Spectinomycin (Trobicin) 2 g IM single dose [B] PLUS (for Chlamydia coverage)

1. Azithromycin (Zithromax) 1 g PO single dose [B] OR

2. Doxycycline (Vibramycin) 100 mg PO bid for 7 days [D]

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