Pathophysiology

Rheumatic heart disease remains an important cause of combined aortic and mitral disease. Between 32 and 50 percent of patients with cardiac manifestations of rheumatic fever have both aortic and mitral disease. In aged patients, calcification can lead to both aortic stenosis and mitral incompetence. Infective endocarditis can extend from either the mitral or aortic valve to the adjacent valve though the inflammatory process. Intravenous drug users may have multivalvular disease. Tricuspid regurgitation often occurs with right ventricular dilation secondary to pulmonary hypertension that may be due to mitral disease or combined aortic and mitral disease.

Blood Pressure Health

Blood Pressure Health

Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Blood pressure is the force of the blood pushing against the walls of your arteries as your heart beats.Learn more...

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