Pathophysiology

Eating disorders are associated with a number of physiologic changes (TabJ┬ži2.8.3i3.). Cachectic patients are relatively well adapted to their chronically deprived, mildly catabolic state. The hypothalamus is affected by low fat intake, which disturbs the reproductive, metabolic, growth, and neurohypophyseal hormones. There is an associated fall in metabolic rate, protein levels are preserved, and cell-mediated immunity tends to be normal. 4

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