Pathophysiology

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Abraham E, Wunderink R, Silverman H: Efficacy and safety of monoclonal antibody to human tumor necrosis factor-alpha in patients with sepsis syndrome. A randomized, controlled, double-blind, multicenter clinical trial. JAMA 273:934, 1995.

Cronin L, Cook DJ, Carlet J: Corticosteroid treatment for sepsis: A critical appraisal and meta-analysis of the literature. Crit Care Med 23:470, 1995.

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Ziegler EJ, Fisher CJ Jr, Sprung CL, et al: Treatment of gram-negative bacteremia and septic shock with HA-1A human monoclonal antibody against endotoxin. A randomized, double-blind, placebo-controlled trial. N Engl J Med 324:429, 1991.

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