Posttransplant Lymphoproliferative Disease PTLD

PTLD can be a consequence of T-cell suppression with long-term cyclosporine use. The overall incidence in lung transplant patients is approximately 8 percent. The disease tends to occur with primary EBV infection following lung transplant. Because younger patients are more likely to be EBV-negative at the time of transplantation, they tend to develop EBV infection and PTLD at a higher rate. Presenting features include isolated lymphadenopathy, painful otitis media (secondary to tonsillar involvement), or a viral-like syndrome. PTLD within 1 year of transplantation is usually localized and can be successfully treated with reduced immunosuppression and high-dose acyclovir, with a relatively good prognosis. In contrast, PTLD after 1 year tends to be disseminated, unresponsive to treatment, and usually fatal.

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Dealing With Back Pain

Dealing With Back Pain

Deal With Your Pain, Lead A Wonderful Life An Live Like A 'Normal' Person. Before I really start telling you anything about me or finding out anything about you, I want you to know that I sympathize with you. Not only is it one of the most painful experiences to have backpain. Not only is it the number one excuse for employees not coming into work. But perhaps just as significantly, it is something that I suffered from for years.

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