Traditional end points have been normalization of blood pressure, heart rate, and urine output. Since these underestimate the degree of remaining hypoperfusion and oxygen debt, more physiologic end points have been investigated18 (Tak]e,2.6.-.7. and TabJ§,,2.6.-8). No therapeutic end point is universally effective, and only a few have been tested in prospective trials, with mixed results. "I9 The goal of resuscitation is to maximize survival and minimize morbidity using objective hemodynamic and physiologic values to guide therapy.
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TABLE 26-7 End Points of Resuscitation
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