This is a tick-borne illness of acute onset and characterized by headache, myalgia, fever, and petechial rash that appears on the palms and soles in two-thirds of patients. Laboratory diagnosis may be made by one of several methods: (1) a fourfold or greater rise in antibody titer to Rickettsia rickettsi. antigen by immunofluorescence antibody, complement fixation, latex agglutination, microagglutination, or indirect hemagglutination antibody test in acute and convalescent specimens taken 4 weeks apart, (2) positive polymerase chain reaction to R. rickettsii, (3) positive immunofluorescence of skin lesion (biopsy) or organ tissue (autopsy), or (4) isolation of R. rickettsii from a clinical specimen.
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Headache Happiness! Stop Your Headache BEFORE IT STARTS. How To Get Rid Of Your Headache BEFORE It Starts! The pain can be AGONIZING Headaches can stop you from doing all the things you love. Seeing friends, playing with the kids... even trying to watch your favorite television shows. And just think of how unwelcome headaches are while you're trying to work.