Septic Shock

Jonathan Jui

Epidemiology

Definitions and Risk Categorization pathophysiology

MoiecuJarPathophys.iSio.Sy., ,o,f„§,epsi,s CJinicaJFeatures

Constitutional

Cardiovascular

Pulmonary

Renal

Hepatic

Hematologic

Endocrine

Acid-Base

Cutaneous

Diagnosis Ancillary, Studies

Treatment

Ai,rwa,y.„a,n,d„ .Respiratory, Management Hemodynamic stabilization Empiric.. .An.t.imicro.bia.l. „Therapy Removalof, ..So,u,,r,c,e..,o,LI,n,f£,c.tiop

Initial ..BaseJine.Assessment

OtherTherapies

N.ew.Agents in..the.Treatment of.Sepsis

Anticytokine..Therapy

TheMeMtrophiJ NitricOxide

OtherAqents

Bibliography

Sepsis is a heterogenous clinical syndrome that can be caused by any class of microorganism. Although both gram-negative and gram-positive bacteria account for the majority of sepsis cases, fungi, mycobacteria, rickettsia, viruses, or protozoans can cause similar presentations. Microbial blood invasion is not essential to the development of sepsis.

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