Sodium Bicarbonate

Sodium bicarbonate is no longer a first-line drug, because it worsens acidosis when administered in the presence of inadequate ventilation and perfusion. It is administered only after epinephrine administration has not improved a clinical situation. An initial dose of 1 meq/kg IV is given only after the airway has been secured, the patient hyperventilated, and CPR initiated. An exception may be a situation where hyperkalemia is a factor, and where metabolic acidosis is severe. Resuscitation drugs are ineffective in the face of severe acidosis and severe alkalosis. In neonates or premature infants, sodium bicarbonate should be diluted 1:1 with sterile water, not saline. Indications for bicarbonate use are the same as for adults.

Essentials of Human Physiology

Essentials of Human Physiology

This ebook provides an introductory explanation of the workings of the human body, with an effort to draw connections between the body systems and explain their interdependencies. A framework for the book is homeostasis and how the body maintains balance within each system. This is intended as a first introduction to physiology for a college-level course.

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