Systemic Toxicity

Morbidity or death from alkali injuries usually results from the complications of direct tissue necrosis, but acid ingestions may result in systemic toxicity from absorption of the acid in addition to local tissue destruction. Significant acid-base disorders, hemolysis, and renal failure may result. In cases of systemic toxicity, traditional critical care principles should be applied to optimize the patient's hemodynamics. Manipulation of serum pH with sodium bicarbonate may be required if the serum pH is consistently below 7.10.

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