Hepatobiliary disease is common in patients with inflammatory bowel disease and includes pericholangitis, chronic active hepatitis, primary sclerosing cholangitis, and cholangiocarcinoma. Gallstones are detected in up to 33 percent of patients with Crohn's disease. Ihe incidence of acute and chronic pancreatitis is increased in patients with Crohn's disease and ulcerative colitis.
Vascular manifestations include thromboembolic disease, vasculitis, and arteritis. Patients with thromboembolic complications have a mortality rate of approximately 25 percent. Ihromboembolic disease is the result of a hypercoagulable state induced in patients with both Crohn's disease and ulcerative colitis and ranks as the third leading cause of death in patients afflicted with these conditions, behind peritonitis and malignancy. Malnutrition and chronic anemia are seen in many patients with long-standing Crohn's disease. Growth retardation can be seen in children. 2
Hyperoxaluria is a common and potentially treatable occurrence in patients with ileal disease and steatorrhea. Ihis results from increased colonic absorption of dietary oxalate and accounts for the occurrence of nephrolithiasis in 20 to 25 percent of patients with ileal disease. Finally, myelodysplastic disease, osteomyelitis, and osteonecrosis have been reported as rare complications of ulcerative colitis and, in particular, Crohn's disease. 34
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Rosacea and Eczema are two skin conditions that are fairly commonly found throughout the world. Each of them is characterized by different features, and can be both discomfiting as well as result in undesirable appearance features. In a nutshell, theyre problems that many would want to deal with.