Analgesics and antipyretics should be administered as indicated. Broad-spectrum antibiotic therapy, ensuring coverage of staphylococcal and streptococcal species, is indicated. When possible, all foreign bodies and appliances should be removed. Initially recommended antibiotics are amoxicillin/clavulanate or ampicillin/sulbactam. Alternatives include vancomycin plus aztreonam.2 If cellulitis is secondary to underlying abscess or osteomyelitis, diagnostic evaluation and treatment for the underlying source is necessary.

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