Treatment Of Diabetic Ketoacidosis

The basic components of DKA treatment are appropriately aggressive fluid and electrolyte replacement (with special attention to potassium) and initiation of insulin therapy, which is essential to arrest further metabolic decompensation (Fig 124-2). Once the diagnosis is confirmed, determinations of the glucose level, venous pH, and electrolyte levels should be made and checked hourly, with further therapy adjusted accordingly. An electrocardiogram is useful for potential evidence of hyperkalemia. If sepsis is suspected as the precipitating factor, blood and urine cultures, lumbar puncture, and chest x-ray should be performed, and antibiotics should be started if indicated.

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