Dermatofibroma (DF) is a reactive proliferation of fibroblasts, histiocytes, and endothelial cells, probably occurring in response to a remote insect bite (20). Lesions are firm, round to oval, from 3 mm to 3 cm, hyperpigmented, and with a smooth surface (Fig. 9). DF may be single or multiple and affect any body site, although the leg ยป is the most frequent location. Pain is a variable feature. Histological examination shows interlacing fascicles of spindle cells, foamy histiocytes, and variable multinu-

d cleated giant cells. An important feature that differentiates DF from malignant fusi- >3

form tumors is the lack of nuclear pleomorphism, necrosis, or mitotic activity.

DF has no malignant potential, therefore, treatment is not necessary (21). Sur- o gical excision is the treatment of choice for painful tumors, for cosmetic reasons, or to rule out malignant melanoma.

Figure 9 Dermatofibroma of the right hand dorsum. The lesion is firm, smooth, and hyperpigmented.
How To Reduce Acne Scarring

How To Reduce Acne Scarring

Acne is a name that is famous in its own right, but for all of the wrong reasons. Most teenagers know, and dread, the very word, as it so prevalently wrecks havoc on their faces throughout their adolescent years.

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