Use of defined SSF media using inert solid support has been considered a very useful method for microbial cultivation for the production of value added products (1,2,3,19,20,25,26,124). The production of L-glutamic acid in SSF with sugarcane bagasse was used as solid inert substrate and a bacterial strain of Brevibacterium sp. was used for the fermentation. The study not only showed good L-glutamic acid synthesis in solid cul-turing but also demonstrated that with media and process parameters manipulation, bacterial strains can also be successfully cultivated in SSF (125). Yield as high as 80 mg glutamic acid per g dry fermented matter was obtained.
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