Dimethyl Dicarbonate

Dimethyl dicarbonate (DMDC) is a colorless liquid that is slightly soluble in water. The compound is very reactive with many substances, including water, ethanol, alkyl and aromatic amines, and sulfhydryl groups (40). The primary target microorganisms for DMDC are yeasts, including Saccharomyces, Zygosaccharomyces, Rhodotorula, Candida, Pichia, Torulopsis, Torula, Endomyces, Kloeckera, and Hansenula. The compound is also bactericidal at 30 to 400 mg/L to a number of species including Acetobacter pasteurianus, E. coli, Pseudomonas aeruginosa, Staphylococcus aureus, several Lactobacillus species, and Pediococ-cus cerevisiae (40). The compound has been shown to be bactericidal against E. coli 0157:H7 in apple cider (41). Molds are generally more resistant to DMDC than yeasts or bacteria.

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