Hydrophobic Interaction

The hydrophobic effect arises from the unfavorable interactions between water molecules and the nonpolar residues of a protein. When a hydrocarbon molecule is introduced into water, it induces changes in water structure, frequently decreasing its entropy. To minimize this unfavorable entropy change, the nonpolar molecules are forced to coalesce into dipoles or globules, reducing their surface of contact with water. As a result, the protein chain is forced to fold into a micellar structure with the hydrocarbon moiety on the inside of the globule and the polar groups on the outside. The removal of the nonpolar residues from contact with water makes a major contribution to the free energy of conformational stabilization. Thus, in this theory, the hydrophobic effect is purely the result of the phobia of water when contacting with hydrocarbons.

Sleeping Sanctuary

Sleeping Sanctuary

Salvation For The Sleep Deprived The Ultimate Guide To Sleeping, Napping, Resting And  Restoring Your Energy. Of the many things that we do just instinctively and do not give much  of a thought to, sleep is probably the most prominent one. Most of us sleep only because we have to. We sleep because we cannot stay awake all 24 hours in the day.

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