Caffeine attains the same concentration in gonadal tissue as in the circulating plasma and may thus reach levels of up to 0.05 mM for very heavy consumers (43). In vitro mutagenicity studies in which positive results are obtained generally involve concentrations at least 100 times greater and are therefore at or above the lethal concentration for humans. At these high concentrations, DNA repair is inhibited, an effect attributable to its purine analog structure. Caffeine may thus be considered a weak mutagen with no significance for humans.

The Mediterranean Diet Meltdown

The Mediterranean Diet Meltdown

Looking To Lose Weight But Not Starve Yourself? Revealed! The Secret To Long Life And Good Health Is In The Foods We Eat. Download today To Discover The Reason Why The Mediterranean Diet Will Help You Have Great Health, Enjoy Life And Live Longer.

Get My Free Ebook

Post a comment