Op

Loss

Gain

Hydrogen atoms

Glycolysis Glucose-6-P

Fructose-l,6-diP Phosphoglyceraldehyde Phosphoglyceric acid Pyruvic acid Lactic acid

Released

Accepted

"SD = substrate dephosphorylation; SP = substrate phosphorylation; OP = oxidative phosphorylation.

Liver

Alanine

Lactic acid

Ammonia Pyruvic acid

Urea Glucose —Glycogen i—t Urea Glucose

Muscle

Glucose Glycogen Protein

Pyruvic acid Amino acids

Lactic acid Alanine

Alanine i

Blood

Figure 11. The role of liver and muscle in gluconeogenesis.

Adipose tissue

Liver

Muscle (and other tissues)

Fats i

Fatty acids

Glycerols

Fats Amino acids

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