Combining Ystr Information And Autosomal Dna Results

In some cases, such as a fingernail scrapping, a missing persons investigation, or a mass disaster reconstruction scenario, results from both Y-STR loci and a limited number of autosomal loci may be obtained. The question might then be asked can this information be combined to increase the rarity of a match since the autosomal data by itself may not be satisfactory? While this is a relatively new area and has not been investigated in detail yet, Sinha et al. (2004) reason that multiplication of the autosomal STR locus profile frequency obtained following the NRC II recommendations (see Appendix VI) and the Y-STR haplotype frequency obtained with a minimal frequency threshold and correction for sampling (as demonstrated in the previous example) is still conservative based on lack of dependence between Y-STR loci and biological independence of chromosomes. Those interested in a detailed discussion of the theoretical issues between joint match probabilities for Y-STRs and autosomal markers should consult a manuscript by Bruce Walsh from the University of Arizona (see http://nitro.biosci.arizona.edu/zdownload/current_ms/ Y-autosomal.pdf).

Was this article helpful?

0 0
Prevent Stuttering

Prevent Stuttering

Are You Suffering From Social Withdrawal? Do People Shun Or Ostracize You Because You Have A Hard Time Getting Some Of Your Words Out? Or Does Your Child Get Teased At School Because They Stutter And Cant Speak Like Everyone Else? If you have answered yes to any of the above, then you are in the tiny percentage of people that stutter.

Get My Free Ebook


Post a comment