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Figure 9.8

Various published allele nomenclatures for DYS439. (a) Sequence from DYS439 spanning the repeat regions used in the various nomenclatures; (b) schematic of allele designation by Ayub et al. 2000 — repeat range is 9-14; (c) schematic of allele designation by Grignani et al. 2000 — repeat range is 16—21; (d) schematic of allele designation by Gonzalez-Neira et al. 2001 — repeat range is 18—23. The most widely accepted designation and what is used in commercial Y-STR hits is (b) — that of Ayub et al. 2000.

studied (Gusmao et al. 2002b). Since the chimpanzees examined in their study did not vary in the other regions outside of the variable core GATA repeat for DYS439, Gusmao and co-workers (2002b) proposed a [GATA]m repeat structure for humans (see Figure 9.8, panel b). This nomenclature has now been adopted for all commercial STR kits typing DYS439.

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