Partial Str Profiles

If the genomic DNA in a sample is severely degraded or PCR inhibitors are present, only a partial STR profile may be obtained (see Chapter 7). Usually the larger STR loci in a multiplex reaction, such as D18S51 and FGA, will be the first to fail on a degraded DNA sample. When only a partial profile is obtained, the significance of a match will go down because there are not as many loci to compare (see Chapter 22). However, the use of mini-plex STR systems with smaller PCR product sizes than those used in commercial STR kits can be used to recover information lost at the larger loci (Butler et al. 2003).

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Stammering Its Cause and Its Cure

Stammering Its Cause and Its Cure

This book discusses the futility of curing stammering by common means. It traces various attempts at curing stammering in the past and how wasteful these attempt were, until he discovered a simple program to cure it. The book presents the life of Benjamin Nathaniel Bogue and his struggles with the handicap. Bogue devotes a great deal of text to explain the handicap of stammering, its effects on the body and psychology of the sufferer, and its cure.

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