The use of reference samples will aid in obtaining calibrated and consistent results among laboratories performing Y-STR testing. The U.S. National Institute of Standards and Technology (NIST) released Standard Reference Material (SRM) 2395 in July 2003 that serves as a human Y chromosome DNA profiling standard. Five male DNA samples are provided with SRM 2395, each of which has been sequenced at over 20 different Y-STR loci including the common core loci present in all commercially available kits.
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