Software For Deciphering Mixture Components

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Computer programs can be used to aid the process of deciphering mixture components and determining mixture ratios. A linear mixture analysis approach was reportedly able to derive estimated mixture ratios from quantitative STR peak information that were similar to known input mixture proportions (Perlin and Szabady 2001). Researchers at the University of Tennessee are also working on algorithms to decipher mixture components in an automated fashion (Wang et al. 2002).

Figure 7.7

Expected peak profiles for 2:1 mixture combinations involving three peaks. These peak profiles assume no overlap with stutter products and homozygote alleles that possess twice the signal strength of each heterozygote allele.

Figure 7.7

Expected peak profiles for 2:1 mixture combinations involving three peaks. These peak profiles assume no overlap with stutter products and homozygote alleles that possess twice the signal strength of each heterozygote allele.

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