There are generally considered to be two stages to validation: developmental validation and internal validation. Developmental validation involves the testing of new STR loci or STR kits, new primer sets, and new technologies for detecting STR alleles. Internal validation, on the other hand, involves verifying that established procedures examined previously under the scrutiny of developmental validation (often by another laboratory) will work effectively in one's own laboratory. Developmental validation is typically performed by commercial STR kit manufacturers and large laboratories such as the FBI Laboratory while internal validation is the primary form of validation performed in smaller local and state forensic DNA laboratories.
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