The resulting PCR products are then separated and detected in order to characterize the STR region being examined. The separation methods used today include slab gel and capillary electrophoresis (CE) (Chapter 12). Fluorescence detection methods have greatly aided the sensitivity and ease of measuring PCR-amplified STR alleles (Chapter 13). The primary instrument platform used in the United States for fluorescence detection of STR alleles is currently the ABI Prism 310 Genetic Analyzer (Chapter 14). After detecting the STR alleles, the number of repeats in a DNA sequence is determined, a process known as sample genotyping (Chapter 15).

The specific methods used for DNA typing are validated by individual laboratories to ensure that reliable results are obtained (Chapter 16) and before new technologies (see Chapter 17) are implemented. DNA databases, such as the one described earlier in this chapter to match Montaret Davis to his crime scene, are valuable tools and will continue to play an important role in law enforcement efforts (Chapter 18).

Stammering Its Cause and Its Cure

Stammering Its Cause and Its Cure

This book discusses the futility of curing stammering by common means. It traces various attempts at curing stammering in the past and how wasteful these attempt were, until he discovered a simple program to cure it. The book presents the life of Benjamin Nathaniel Bogue and his struggles with the handicap. Bogue devotes a great deal of text to explain the handicap of stammering, its effects on the body and psychology of the sufferer, and its cure.

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