Using The Counting Method With Lineage Markers

Lineage markers include mitochondrial DNA (see Chapter 10) and Y chromosome haplotypes (see Chapter 9) that are transferred directly from generation to generation either from mother to child in the case of mitochondrial DNA or from father to son in the case of the Y chromosome. As described in the earlier chapters, the counting method in conjunction with an upper bound confidence limit is typically used with mtDNA or Y chromosome haplotypes. The counting method relies on the size of the database and involves counting the number of times the profile (haplotype) has been observed within the database. A frequency estimate with a confidence interval is then made based on this count (see D.N.A. Box 10.3).


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