Oooc oc

Nuclear transplantation amphibian cloning, 1:161-163 as gene therapy tool, 2:73 mammal cloning, 1:162,

1:163-164 transgenic animals, 4:124-126 See also In vitro fertilization Nuclease enzymes, 3:112-115 crossing-over role, 1:195, 1:196 defined, 1:31, 4:53 deoxyribonucleases, 3:112,

3:113-114 DNase, 1:201, 1:220, 3:221 endonucleases, 3:112-113, 3:113,

3:114-115 exonucleases, 3:112-113,

3:113-115, 3:113 function, 1:31, 3:112 hydrolysis reactions, 3:113, 3:114 lyase reactions, 3:113 ribonucleases, 3:112, 3:114-115 structure preferences, 3:112-113 See also Restriction enzymes Nucleic acid defined, 2:49, 3:187

3:104, 3:105 electrophoresis to separate, 2:49 Nucleocapsids, HIV, 2:152 Nucleoids defined, 1:139, 2:14 E. colt, 1:141

structure and function, 2:14-15, 2:112

Nucleolar organizer, 3:123-124 Nucleoli, 1:105, 1:111 Nucleolus defined, 4:58

ribosome synthesis, 4:43, 4:58 structure and function, 3:120, 3:121, 3:123-124 Nucleomorphs, overlapping genes,

3:136 Nucleoplasm defined, 3:121

structure and function, 3:121, 3:122-123 Nucleoporins, 3:125-126 Nucleoside analogues, 4:171 Nucleoside triphosphates, defined,

1:230 Nucleosides defined, 4:41

and DNA structure, 1:215-220 structure, 3:115, 3:117 Nucleosomes, 1:134 defined, 4:111

structure and function, 1:126, 1:133-134, 4:111, 4:114 Nucleotide analogs azidothymidine, 2:155-156 ganciclovir, 3:17 Nucleotide excision repair (NER),

1:244-246, 1:245, 1:247 Nucleotides, 3:115-119

defined, 1:13, 2:22, 3:82, 4:9 and DNA structure, 1:216-220,

number in human genome, 1:73,

4:7, 4:13 proportions, Chargaff s studies,

1:250-251, 4:172 radioactive labeling, 1:220 in RNA, 4:46-47, 4:47, 4:48,

4:49, 4:54, 4:109, 4:109, 4:135 RNA, evolution of, 2:22-25 structure, 3:115, 3:116, 3:117 See also Base pairs; DNA sequencing; Genetic code; RNA sequencing Nucleus, 1:111, 3:119-126, 3:121 Cajal bodies, 3:120, 3:124, 4:50 centrosomes, 3:121 chromatin, 3:120, 3:120, 3:121 chromosomal territories,

3:121-122, 3:122 discovery, 3:119 gems, 3:124

interchromatin compartment,

3:120, 3:121, 3:122-123, 3:122 intermediate filaments, 3:120,

3:121 microtubules, 3:121 nuclear lamina, 3:120, 3:121,

3:121, 3:125 nuclear pores, 3:121 nucleolus, 3:120, 3:121,

3:123-124 nucleoplasm, 3:121, 3:122-123 origin of term, 3:119 PML bodies, 3:124-125 polyglutamine aggregates in,

4:151-152 speckles, 3:120, 3:125 structure, 105, 1:112, 1:132-133, 2:112, 3:119-121, 3:120, 3:121, 4:12

techniques for studying, 3:121,

3:122, 3:124, 3:125 See also Endoplasmic reticulum; Ribosomes Nutrition (diet)

amino acid requirements, 3:41

antioxidants in, 3:89

and birth defects, 1:78

and cancer, 1:92

and cancer of breast, 1:91

and colon cancer, 1:170

as disease treatment tool, 2:118

of early humans, 3:63, 3:68-69

familial hypercholesterolemia and, 2:57 and hormone regulation, 2:164 and longevity, 1:6 and phenylketonuria, 2:55-56,

2:99, 2:119, 3:176 to treat metabolic diseases, 3:39, 3:43, 3:44, 3:45

Obesity and cardiovascular disease, 1:101 and diabetes, 1:210 "Disease Model" mouse strains, 3:62

O'Brien, Chloe, 3:186 O'Brien, Stephen J., 1:189 Obsessive-compulsive disorder

(OCD), 3:213, 3:215 Occipital cortex, 1:170 Odorant receptors, signal transduc-tion role, 4:89

01 (osteogenesis imperfecta), 2:132 Oil spills, bioremediation, 1:59,

1:60, 1:61, 1:62, 4:129 Oils, genetically engineered, 1:10 Okazaki fragments, 4:14, 4:15, 4:16,

4:17, 4:18 Oligogenic traits, 1:178 Oligonucleotide synthesizers,

1:176-177, 3:155 Oligonucleotides, antisense, 4:183 Omenn syndrome, 4:76 Omphalocele, defined, 2:132 Oncogenes, 3:127-131 and cancer growth, 1:95,

1:99-100 and cell cycle regulation,

1:107-108, 4:169 defined, 1:99, 4:34 as dominant, 3:130 early research, 3:127 growth-signaling pathways and,

3:128, 3:129-130 interactions with environment, 1:180

multiple genetic hits, 3:131 mutations and, 3:98 proto-oncogenes, 3:127,

3:128-129, 4:152 retroviral role, 4:34, 4:38

Was this article helpful?

0 0
10 Ways To Fight Off Cancer

10 Ways To Fight Off Cancer

Learning About 10 Ways Fight Off Cancer Can Have Amazing Benefits For Your Life The Best Tips On How To Keep This Killer At Bay Discovering that you or a loved one has cancer can be utterly terrifying. All the same, once you comprehend the causes of cancer and learn how to reverse those causes, you or your loved one may have more than a fighting chance of beating out cancer.

Get My Free Ebook


Post a comment