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Figure 5. Domain structure of an acidic activation protein. This protein enhances the ability of general transcription factors to bind to the promoter.

Acidic activation domain

Gene regulatory « protein


DNA binding domain

Regulatory element



genes specify large regions of an animal's body plan. Mutations in these genes can transform one body part into another. For instance, a mutation in the antennapedia gene of fruit flies will convert antennae to legs. Thus, expression of a single gene can trigger the expression of a whole battery of genes.

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