Hogan, B., et al. Manipulating the Mouse Embryo: A Laboratory Manual, 2nd ed. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press, 1994.

Joyner, A., ed. Gene Targeting: A Practical Approach, 2nd ed. New York: Oxford University Press, 1999.

Torres, R. M., and R. Kuhn. Laboratory Protocols for Conditional Gene Targeting. New York: Oxford University Press, 1997.

Gene Therapy

Gene therapy is a new and largely experimental branch of medicine that uses genetic material (DNA) to treat patients. Researchers hope one day to use this therapy to treat several different kinds of diseases. While rapid progress has been made in this field in recent years, very few patients have been successfully treated by gene therapy, and a great deal of additional research remains to be done to bring these techniques into common use.

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