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Cycle Sequencing 198

Cystic Fibrosis 199

Development, Genetic Control of 204

Diabetes 209

Disease, Genetics of 213

DNA 215

DNA Footprinting 220

DNA Libraries 222

DNA Microarrays 225

DNA Polymerases 230

DNA Profiling 233

DNA Repair 239

DNA Structure and Function, History . 248

DNA Vaccines 253

Down Syndrome 256

Photo Credits 259

? Glossary 263

Topical Outline 281

Index 287

VOLUME 2_

For Your Reference v

List of Contributors xiii

Educator 1

Embryonic Stem Cells 3

Epidemiologist 6

Epistasis 7

Escherichia coli (E. coli bacterium) 9

Eubacteria 11

Eugenics 16

Evolution, Molecular 21

Evolution of Genes 26

Eye Color 31

Fertilization 33

Founder Effect 36

Fragile X Syndrome 39

Fruit Fly: Drosophila 42

Gel Electrophoresis 45

Gene 50

Gene and Environment 54

Gene Discovery 57

Gene Expression: Overview of Control . . 61

Gene Families 67

Gene Flow 70

Gene Targeting 71

Gene Therapy 74

Gene Therapy: Ethical Issues 80

Genetic Code 83

Genetic Counseling 87

Genetic Counselor 91

Genetic Discrimination 92

Genetic Drift 94

Genetic Testing 96

Genetic Testing: Ethical Issues 101

Genetically Modified Foods 106

Geneticist 110

Genetics 111

Genome 112

Genomic Medicine 118

Genomics 120

Genomics Industry 123

Genotype and Phenotype 125

Growth Disorders 129

Hardy-Weinberg Equilibrium 133

Hemoglobinopathies 136

Hemophilia 141

Heterozygote Advantage 146

High-Throughput Screening 149

HIV 150

Homology 156

Hormonal Regulation 158

HPLC: High-Performance Liquid

Chromatography 165

Human Disease Genes, Identification of . 167

Human Genome Project 171

Human Immunodeficiency Virus 178

Huntington's Disease 178

Hybrid Superiority 178

Immune System Genetics 178

Imprinting 183

In situ Hybridization 186

Inbreeding 189

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