Box 222 Biochemistry In Medicine

Curing African Sleeping Sickness with a Biochemical Trojan Horse

African sleeping sickness, or African trypanosomiasis, is caused by protists (single-celled eukaryotes) called trypanosomes (Fig. 1). This disease (and related trypanosome-caused diseases) is medically and economically significant in many developing nations. Until recently, the disease was virtually incurable. Vaccines are ineffective, because the parasite has a novel mechanism to evade the host immune system.

FIGURE 1 Trypanosoma brucei rhodesiense, one of several trypanosomes known to cause African sleeping sickness.

Ornithine

Diabetes 2

Diabetes 2

Diabetes is a disease that affects the way your body uses food. Normally, your body converts sugars, starches and other foods into a form of sugar called glucose. Your body uses glucose for fuel. The cells receive the glucose through the bloodstream. They then use insulin a hormone made by the pancreas to absorb the glucose, convert it into energy, and either use it or store it for later use. Learn more...

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