1

FIGURE 2-3 Common hydrogen bonds in biological systems. The hydrogen acceptor is usually oxygen or nitrogen; the hydrogen donor is another electronegative atom.

slightly more electronegative than hydrogen and thus the C—H bond is only very weakly polar. The distinction explains why butanol (CH3(CH2)2CH2OH) has a relatively high boiling point of 117 °C, whereas butane (CH3(CH2)2CH3) has a boiling point of only -0.5 °C. Bu-tanol has a polar hydroxyl group and thus can form intermolecular hydrogen bonds. Uncharged but polar bio-molecules such as sugars dissolve readily in water because of the stabilizing effect of hydrogen bonds between the hydroxyl groups or carbonyl oxygen of the sugar and the polar water molecules. Alcohols, aldehydes, ketones, and compounds containing N—H bonds all form hydrogen bonds with water molecules (Fig. 2-4) and tend to be soluble in water.

Hydrogen bonds are strongest when the bonded molecules are oriented to maximize electrostatic interaction, which occurs when the hydrogen atom and the two atoms that share it are in a straight line—that is, when the acceptor atom is in line with the covalent bond between the donor atom and H (Fig. 2-5). Hydrogen bonds are thus highly directional and capable of hold-

Diabetes 2

Diabetes 2

Diabetes is a disease that affects the way your body uses food. Normally, your body converts sugars, starches and other foods into a form of sugar called glucose. Your body uses glucose for fuel. The cells receive the glucose through the bloodstream. They then use insulin a hormone made by the pancreas to absorb the glucose, convert it into energy, and either use it or store it for later use. Learn more...

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