Anterograde Tracers

Anterograde tracers, such as 3H amino acids or WGA-horseradish peroxidase (HRP), are taken up by the thousands of cell bodies within the injection site, transported anterogradely in different compartments through the axon, and accumulated along the axonal membrane and/or at the terminal specializations. Histological processing reveals label in structures that receive connections from the injected region (Fig. 6). Recently, a new generation of glycoconjugate antero-grade tracers (biocytin, biotinylated dextran amine, and kidney bean lectin) have been introduced that bind to the plasmalemma and, after appropriate histologi-cal processing, result in morphologically detailed images of axon structure, including branch points and fine terminal specializations.

Anxiety and Depression 101

Anxiety and Depression 101

Everything you ever wanted to know about. We have been discussing depression and anxiety and how different information that is out on the market only seems to target one particular cure for these two common conditions that seem to walk hand in hand.

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