Apolipoproteins arise from local synthesis or filtration from plasma, although the respective amount remains unclear. According to current views, apolipoprotein E (apoE) is the main apolipoprotein produced and secreted by astrocytes within the brain parenchyma. ApoE is presumably involved in the redistribution of lipids among cells. Other apolipoproteins appear to be involved in brain lipid transport and homeostasis, such as ApoJ and ApoD. ApoD is found mainly in oligodendrocytes and astrocytes. Irregular lipoprotein metabolism, possibly related to special isoforms, may be involved in several neurodegenerative diseases, especially Alzheimer's disease.

Breaking Bulimia

Breaking Bulimia

We have all been there: turning to the refrigerator if feeling lonely or bored or indulging in seconds or thirds if strained. But if you suffer from bulimia, the from time to time urge to overeat is more like an obsession.

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