Delta Receptors

Delta receptors were first found following the discovery of the enkephalins, their endogenous ligand. Early attempts to define the pharmacology of the delta receptors were limited by the lability of the enkephalins and their limited selectivity. The development ofhighly selective delta peptides, and recently organic compounds, has revealed important actions. Like mu receptors, activation of delta receptors produces analgesia but with far less respiratory depression and constipation. There is evidence for subtypes of delta receptors based on a series of antagonists, but functional splice variants have not been reported. The full functional significance of delta receptor systems is not entirely established.

Constipation Prescription

Constipation Prescription

Did you ever think feeling angry and irritable could be a symptom of constipation? A horrible fullness and pressing sharp pains against the bladders can’t help but affect your mood. Sometimes you just want everyone to leave you alone and sleep to escape the pain. It is virtually impossible to be constipated and keep a sunny disposition. Follow the steps in this guide to alleviate constipation and lead a happier healthy life.

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