Ligand Gated Ion Channels

Ligand-gated ion channels are activated upon the binding of a neurotransmitter to the ion channel and are involved in fast synaptic transmisssion in the nervous system. Many of the ion channels in Table II have a wide tissue distribution outside of the nervous system and have other functions beyond synaptic transmission. These neurotransmitters include acetyl-choline, g-aminobutyric acid (GABA), glycine, glutamate, and serotonin (5-hydroxytryptophan), and the ion channels are more commonly referred to as receptors. Several of these neurotransmitters also activate a second distinct type of receptor. This second receptor type is a heptahelical receptor that produces intracellular second messengers through the modulation of G proteins. Most commonly in the context of glutamate receptors, the ligand-gated ion channel is referred to as an ionotropic receptor, whereas the G

Ion channel Ion selectivity

Breaking Bulimia

Breaking Bulimia

We have all been there: turning to the refrigerator if feeling lonely or bored or indulging in seconds or thirds if strained. But if you suffer from bulimia, the from time to time urge to overeat is more like an obsession.

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