Enteric glial cells establish the perimeter of the myenteric plexus and partition myenteric ganglia into compartments. The surfaces of enteric glia are devoid of laminin and are only in contact with laminin where their end feet are in contact with the basal lamina. The enteric glial cells are packed with 10-nm intermediate filaments, and as such enteric glia are rich in glial fibrillary acidic protein (GFAP). GFAP-positive cells cannot be identified exclusively as enteric glial cells because PNS Schwann cells also express GFAP.

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