Host Characteristics

The age of the patient is also a factor in the severity of neurobehavioral deficits. The incidence of histopa-thologically more aggressive tumors, such as glioblas-toma multiforme, increases with age. However, histopathologically less malignant tumors, such as anaplastic astrocytoma, also behave more aggressively in the older patient. Older patients are also at higher risk for having other concurrent neurodegenerative illnesses, such as Parkinson's disease or vascular disease. Finally, very old and very young patients may be more sensitive to the toxic side effects of treatment.

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