Cobalamin Deficiency

A lack of cobalamin, or vitamin B12, is a well-known cause of the spinal cord disease known as subacute combined degeneration. Less commonly, cobalamin deficiency may cause neurobehavioral manifestations ranging from personality change to dementia. As in the spinal cord, the brain white matter is affected by vitamin B12 deficiency, a finding that may be visible on MRI scanning. Replacement of cobalamin can result in substantial clinical improvement and resolution of neuroradiologic abnormalities.

All About Alzheimers

All About Alzheimers

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