The use of high-dose glucocorticoids has been shown to produce dramatic reductions in cerebral edema in certain conditions. These agents may stabilize and accelerate repair of the BBB, reduce capillary permeability, improve brain availability of glucose, and alter production of chemical mediators that lead to cerebral edema. Glucocorticoids may also decrease production of CSF, thereby reducing ICP. These agents are particularly effective in edema resulting from tumors and meningitis. Most clinical studies have failed to demonstrate a benefit of glucocorticoids in the setting of TBI. The use of high-dose glucocorticoids may have detrimental effects when used to treat ischemic edema.

Conquering Fear In The 21th Century

Conquering Fear In The 21th Century

The Ultimate Guide To Overcoming Fear And Getting Breakthroughs. Fear is without doubt among the strongest and most influential emotional responses we have, and it may act as both a protective and destructive force depending upon the situation.

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