Glossary

dopamine A neurotransmitter important in modulation of movement and behavior.

major histocompatability complex Antigen presenting proteins expressed on the surface of most cells; specific immunity to viruses is dependent on recognition of non self (viral) peptide fragments presented in the context of these proteins.

negative-strand RNA virus A virus with a genome composed of ribonucleic acid that serves as a template for transcription of messenger RNA-encoding viral proteins. Its minimal infectious unit is composed of the viral genome, nucleoprotein, phosphoprotein, and polymerase.

reverse transcription polymerase chain reaction A method for logarithmically amplifying ribonucleic acid sequences to facilitate cloning and/or detection of targets present only at low frequency.

Borna disease virus (BDV) is a novel neurotropic RNA virus that infects a wide variety of warm-blooded animal species. Infection may be asymptomatic or result in a broad spectrum of behavioral disorders, dependent on the age of the host and its immune response. Although the question of human BDV infection remains to be resolved, burgeoning interest in this unique pathogen has provided tools for exploring the pharmacology and neurochemistry of neuropsychiatric disorders potentially linked to infection. Analysis of rodent

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