limbic system A group of subcortical structures (such as the hypothalamus, the hippocampus, and the amygdala) of the brain that are concerned especially with emotion and motivation.

melancholia A mental condition characterized by extreme depression, bodily complaints, and often hallucinations and delusions.

neurotransmitter A substance (as norepinephrine or acetylcho-line) that transmits nerve impulses across a synapse.

proband An individual being studied in a genetic investigation.

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