Brain tumors, whether benign or malignant, typically involve widespread cerebral areas that include both gray and white matter. This is particularly true of those tumors that induce surrounding edema and thus affect even more adjacent tissue. Thus, neoplasms in general are not well suited to considering the effects of discrete focal lesions on brain function. Nevertheless, some tumors have a predilection for gray or white matter, at least early in their course, and some preliminary clinical correlations can be made.

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